Read the detailed Instructions for Use that come with your Humulin R U-500.
Take Humulin R U-500 exactly as your healthcare provider tells you to. Your healthcare provider should show you how much Humulin R U-500 to use and when to use it.
Know the dose of Humulin R U-500 you use. Do not change your dose unless your healthcare provider tells you to.
Check your insulin label each time you give your injection to make sure you are using the correct insulin.
Humulin R U-500 KwikPen: The U-500 KwikPen is specially made to dial and deliver doses of Humulin R U-500 insulin. Do not use any syringe to remove Humulin R U-500 insulin from your U-500 KwikPen. The markings on certain syringes will not measure your dose correctly. A severe overdose can happen, causing low blood sugar, which may put your life in danger.
Humulin R U-500 vial: There is a special U-500 insulin syringe to measure Humulin R U-500. Use only a U-500 insulin syringe to draw up and inject your Humulin R U-500. If you do not use the right syringe type, you may take the wrong dose of Humulin R U-500. This can cause you to have too low blood sugar (hypoglycemia) or too high blood sugar (hyperglycemia). Your healthcare provider should show you how to draw up Humulin R U-500.
Use Humulin R U-500 30 minutes before eating a meal.
Inject Humulin R U-500 under your skin (subcutaneously). Do not use Humulin R U-500 in an insulin pump or inject Humulin R U-500 into your vein (intravenously) or your muscle (intramuscularly).
Do not mix Humulin R U-500 with any other type of insulin or liquid medicine.
Change your injection site with each dose.
Check your blood sugar levels. Ask your healthcare provider what your blood sugar level should be and when you should check your blood sugar.
Your dose of Humulin R U-500 may need to change because of changes in your level of exercise, weight, or diet, or because of increased stress, illness, or other medicines you take.
Keep Humulin R U-500 and all medicines out of the reach of children.