Dosing and storing Humulin R U-500


- Injection Sites Whether you use the U-500 KwikPen or a U-500 vial and syringe, you’ll want to rotate the site each time you inject. Always be sure to wipe your skin with an alcohol swab and let the area dry first.
- Confirm your dose with your doctor For a handy reference, please have your doctor write down your daily dosing schedule.
- Administer Humulin R U-500 subcutaneously two or three times daily 30 minutes before a meal into the thigh, upper arm, abdomen, or buttocks.
- Be sure to refer to the Instructions for Use that came with your U-500 KwikPen or vial. Of course, if you have any questions, please be sure to talk to your doctor.
- How should I store Humulin R U-500? Keep Humulin R U-500 away from heat and direct sunlight and out of the reach of children. An unopened pen or vial should be kept in the refrigerator and discarded after the expiration date stamped on the label.
- Storing the Humulin R U-500 KwikPen Once opened, do not refrigerate the Humulin R U-500 KwikPen. Throw away the pen you are using after 28 days, even if there is still insulin left.*
- Storing the Humulin R U-500 vial Do not use if it has been frozen. An unopened vial should be kept in the refrigerator until the expiration date. An open vial can be stored at room temperature and must be thrown away within 40 days of opening even if insulin remains.**
*Please see the Instructions for Use included with your pen. Do not freeze or use insulin that has been previously frozen. Do NOT withdraw insulin from the pen using any syringe.
**Please see the Instructions for Use included with your vial. Do not freeze or use insulin that has been previously frozen.