Leading endocrinologists discuss experience with high-dose patients
OR CHOOSE A CHAPTER FROM THE MENU BELOW
Humulin R U-500 is a concentrated human insulin indicated to improve glycemic control in adults and children with diabetes mellitus requiring more than 200 units of insulin per day.
Limitations of Use: The safety and efficacy of Humulin R U-500 used in combination with other insulins, or when delivered by continuous subcutaneous infusion, has not been determined.
Humulin R U-500 is contraindicated during episodes of hypoglycemia and in patients hypersensitive to Humulin R U-500 or any of its excipients.
DO NOT transfer Humulin R U-500 from the KwikPen into any syringe for administration. Overdose and severe hypoglycemia can occur.
Never share a KwikPen or U-500 syringe between patients, even if the needle is changed, to avoid risk of transmission of blood-borne pathogens.
Other adverse reactions include allergic reactions, lipodystrophy, injection site reactions, pruritus, and rash.
For more information, see Full Prescribing Information, including Patient Information and Instructions for Use for the KwikPen and vial.