Introducing the easy-to-use U-500 KwikPen

Watch this video for more information

No dose conversion

The new Humulin R U-500 KwikPen dials and doses the insulin units prescribed. Similar to other insulin pens,1 there's no dose conversion with the U-500 KwikPen. If you prescribe 100 units of U-500 with this KwikPen, the patient will dial to 100 to get the insulin needed. In contrast, if you prescribe 100 units with the U-500 vial and the U-100 insulin syringe, the patient would draw to the 20-unit marking.

Designed for high-dose insulin needs2

Only1 the Humulin R U-500 KwikPen is designed to deliver up to 300 units in a single injection for the high-dose needs of severely insulin-resistant patients. It also holds 1500 units of insulin in every pen—the same amount as five U-100 pens.1

How it’s different from other pens3

The aqua pen body makes the U-500 KwikPen stand out from other insulin pens to reduce the potential for confusion.3 In addition, it’s the only pen that dials in 5-unit increments.1

How it’s similar to other KwikPens

Although it holds more units of insulin, the U-500 KwikPen is the same size as other KwikPens.


  1. Data on file, Lilly USA, LLC. HM20151210d.
  2. Data on file, Lilly USA, LLC. HM20151210a.
  3. Data on file, Lilly USA, LLC. HM20151210e.